Objective: This study evaluates the role of Community Health Nurses (CHNs) in strengthening prevention, detection, and management of non-communicable diseases (NCDs) in rural districts of Chhattisgarh, India, within the framework of the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS).

Methods: A cross-sectional mixed-method study was conducted in six rural blocks across three districts, involving 45 CHNs and 150 adult patients with diagnosed or high-risk NCDs. Quantitative data were obtained using structured questionnaires, facility readiness checklists, and service utilization records, while qualitative insights were gathered from 18 key informant interviews and six focus group discussions. Quantitative analyses included descriptive statistics and correlation analysis, and qualitative data underwent thematic content analysis.

Results: Over 80% of CHNs routinely conducted community-based screening for hypertension and diabetes, 74% provided lifestyle counselling, and 65% actively followed up defaulters through home visits. Facilities with dedicated CHNs recorded higher patient follow-up compliance and better essential drug availability. Key challenges included limited NCD-specific training, inconsistent medicine supplies, and high patient loads in tribal areas. CHN knowledge, attitudes, and practices were positively associated with patient adherence, follow-up rates, and satisfaction.